Nephrotic syndrome is a kidney disorder that causes body to excrete too much protein in your urine. Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels inthe kidneys that filter waste and excess water from blood. Nephrotic syndrome causes swelling (edema), particularly in feet , ankles, and increases the risk of other health problems.

Symptoms

Signs and symptoms of nephrotic syndrome include:

  • Severe swelling (edema), particularly around your eyes and in ankles and feet
  • Foamy urine, which may be caused by excess protein in urine
  • Weight gain due to excess fluid retention
  • Fatigue
  • Loss of appetite

Causes

Nephrotic syndrome is usually caused by damage to the clusters of tiny blood vessels (glomeruli) of kidneys.The glomeruli filter blood as it passes through kidneys, separating things body needs from those it doesn’t. Healthy glomeruli keep blood protein (mainly albumin) — which is needed to maintain the right amount of fluid in the body — from seeping into the urine. When damaged, glomeruli allow too much blood protein to leave body, leading to nephrotic syndrome.

Many diseases and conditions can cause glomerular damage and lead to nephrotic syndrome, including:

  • Diabetic kidney disease. Diabetes can lead to kidney damage (diabetic nephropathy) that affects the glomeruli.
  • Minimal change disease. This is the most common cause of nephrotic syndrome in children. Minimal change disease results in abnormal kidney function, but when the kidney tissue is examined under a microscope, it appears normal or nearly normal. The cause of the abnormal function typically can’t be determined.
  • Focal segmental glomerulosclerosis. Characterized by scattered scarring of some of the glomeruli, this condition may result from another disease or a genetic defect or occur for no known reason.
  • Membranous nephropathy. This kidney disorder is the result of thickening membranes within the glomeruli. The exact cause of the thickening isn’t known, but it’s sometimes associated with other medical conditions, such as hepatitis B, malaria, lupus and cancer.
  • Systemic lupus erythematosus. This chronic inflammatory disease can lead to serious kidney damage.
  • Amyloidosis. This disorder occurs when substances called amyloid proteins accumulate in your organs. Amyloid buildup often affects the kidneys, damaging their filtering system.
  • Blood clot in a kidney vein. Renal vein thrombosis, which occurs when a blood clot blocks a vein connected to the kidney, can cause nephrotic syndrome.

Traditional view:

Nephrotic syndrome is not directly mentioned with a name in the Ayurvedic classical text books. Because of main characteristic features of albuminuria with hyperlipidemia associated with oedema it may be included under the title of prameha (a disease of urinary system with altered composition, frequency and quantity of urine). Albuminuria makes urine concentrated, viscid or dense. These features can be correlated with sandrameha a subtype of prameha. According to ayurveda, kapha vata dominating tridosha as well as rasa, mutra, udaka, ojas are the components get vitiated in this disease. Any disease even if it is not described in ancient text can be managed by applying the fundamental principles related to pathogenesis and treatment in Ayurveda. On this basis nephrotic syndrome indicates the aggravation of kapha dosha along with vitiation of rasadhatu, ojas, Mutra and udaka involving mutravaha srotas and udakavaha srotas .Ayurvedic treatment aims at balancing these dosas and restore the function of kidneys.

At Haridra we treats Nephrotic syndrome successfully with the help of traditionally prepared ayurveda and siddha medications. Initially cleansing is done to remove the excessively aggrevated dosas , then traditionally prepared classical ayurveda and siddha medicines are given to restore the health and proper functioning of kidneys.

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